Malcolm Le Grice studied painting at the Slade School of Fine Art, London, and began to make film, video and computer works in the mid-60s. Together with David Curtis, he founded the London Film Makers Cooperative in 1968. Out of the Co-Op emerged Filmaktion: a group of radical performance artists and filmmakers, of which Le Grice was part.
He has exhibited extensively in museums and film festivals including: Paris Biennale No.8, Paris, 1973; Une Histoire du Cinema, Paris, 1976; Documenta 6, Kassel, 1977; X-Screen at the MUMOK, Vienna, 2004; Behind the Facts. Interfunktionen 1968-1975, Fundació Joan Miró, Barcelona, 2004; Performa13, New York, 2013. Screenings have been held at Museum of Modern Art, New York; Louvre, Paris; Tate Modern and Tate Britain, London.